Training & Education III
Integrated Molecular & Experimental Pathology
Biological structure shapes function, and function is executed by molecular programs. Building on this principle, we integrate experimental histopathology with advanced molecular profiling to explain disease mechanisms with precision. Tissue phenotypes are linked to cellular states, gene-expression programs, and genetic alterations, creating a coherent path from morphology to molecular drivers.
This approach brings together classical microscopy, next-generation sequencing, and a diverse suite of organoid and reliable mouse models, allowing direct causal dissection of how diseases initiate, progress, and interact with their microenvironment. These in vivo systems provide a mechanistic scaffold that grounds molecular observations in physiologic biology.
Core elements include quantitative digital pathology, analysis of single-cell–based datasets, mechanistic validation of signaling pathways in experimental models, and translation of integrated findings into actionable biological insight.
