Publication

Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency.

주저자 : Kwon JW, Oh JS, Seok SH, An HW, Lee YJ, Lee NY, Ha TH, Kim HA, Yoon GM, Kim SE, Oh PR, Lee SH, Voon DC, Kim DY, Park JW.

Mol Cancer

2023

The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer.

An HW, Seok SH, Kwon JW, Choudhury AD, Oh JS, Voon DC, Kim DY, Park JW.

Cell Rep.

2022

A synergistic partnership between IL-33/ST2 and Wnt pathway through Bcl-xL drives gastric cancer stemness and metastasis.

Kwon JW, Seok SH, Kim S, An HW, Choudhury AD, Woo SH, Oh JS, Kim JK, Voon DC, Kim DY, Park JW.

Oncogene.

2022

Smad4 and p53 synergize in suppressing autochthonous intestinal cancer.

Park JW, Seo MJ, Cho KS, Kook MC, Jeong JM, Roh SG, Cho SY, Cheon JH, Kim HK.

Cancer Med.

2022

MiR-30a and miR-200c differentiate cholangiocarcinomas from gastrointestinal cancer liver metastases.

Park JW, Jeong JM, Cho KS, Cho SY, Cheon JH, Choi DH, Park SJ, Kim HK.

PLoS One.

2021

In vivo CRISPR-Cas9 knockout screening using quantitative PCR identifies thymosin beta-4 X-linked that promotes diffuse-type gastric cancer metastasis.

An HW, Kim SY, Kwon JW, Seok SH, Woo SH, Kim DY, Park JW.

Mol Carcinog

2021

Multi-omics analysis identifies pathways and genes involved in diffuse-type gastric carcinogenesis induced by E-cadherin, p53, and Smad4 loss in mice.

Park JW*, Min-Sik Kim*, Dominic C. Voon, Su-Jin Kim, Jingi Bae

Molecular Carcinogenesis

2018

Downregulation of TXNIP leads to high proliferative activity and estrogen-dependent cell growth in breast cancer.

Park JW, Su Hyung Lee, Gye-Hyung Woo, Hyo-Jung Kwon, and Dae-Yong Kim.

Biochemical and Biophysical Research Communications.

2019

AHNAK Loss in Mice Promotes Type II Pneumocyte Hyperplasia and Lung Tumor Development.

Park JW*, Il Yong Kim*, Ji Won Choi, Hee Jung Lim, Jae Hoon Shin.

Molecular Cancer Research.

2018

Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.

Soo Young Cho*, Park JW*, Yang Liu*, Young Soo Park, Ju Hee Kim

Gastroenterology

2017

Proteogenomic analysis of NCC-S1M, a gastric cancer stem cell-like cell line that responds to anti-PD-1.

Park JW*, Hyejin Um*, Hanna Yang, Woori Ko, Dae-Yong Kim, Hark Kyun Kim.

Biochemical and Biophysical Research Communications.

2017

Sca-1 enriches for a cancer stem cell-like subpopulation in mouse gastric cancer.

Park JW, Park JM, Park DM, Kim DY, Kim HK.

Stem cells.

2016

Osteopontin depletion decreases inflammation and gastric epithelial proliferation during Helicobacter pylori infection in mice.

Park JW, Lee SH, Go du M, Kim HK, Kwon HJ, Kim DY.

Laboratory Investigation.

2015

Establishment and characterization of metastatic gastric cancer cell lines from murine gastric adenocarcinoma lacking Smad4, p53, and E-cadherin.

Park JW, Park DM, Choi BK, Kwon BS, Seong JK, Green JE.

Molecular Carcinogenesis.

2015

Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis.

Park JW, Jang SH, Park DM, Lim NJ, Deng C, Kim DY.

Molecular Carcinogenesis.

2014

Preclinical efficacy testing for stomach and liver cancers.

Park JW, Baek NS, Lee SC, Oh SJ, Jang SH, Kim IH.

Cancer Research and Treatment.

2014

MALDI MS Profiles Distinguish ER-Negative Breast Cancers from Lung Adenocarcinoma.

Michelle L*, Park JW*, Jamie L Allen, Oleg Chertov, Dae Yong Kim.

Journal of Proteomics and Bioinformatics.

2013

Matrix-assisted laser desorption/ionization mass spectrometry reveals decreased calcyclin expression in small cell lung cancer.

Lee HS*, Park JW*, Chertov O, Colantonio S, Simpson JT, Fivash MJ *First authors, equally contributed

Pathology International.

2012