서울대학교 수의과대학 실험동물의학 (박준원 교수)Laboratory Animal Medicine, CVM, Seoul National University (PI: Jun Won Park)

Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway

Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity

Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines

Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cel

Immune evasion of dormant disseminated tumor cells is due to their scarcity and can be overcome by T cell immunotherapies

THBS2 + cancer-associated fibroblasts promote EMT leading to oxaliplatin resistance via COL8A1-mediated PI3K/AKT activation in

Microbiota alters the metabolome in an age- and sex- dependent manner in mice

Mdm2 requires Sprouty4 to regulate focal adhesion formation and metastasis independent of p53

Characterization of the landscape of the intratumoral microbiota reveals that Streptococcus anginosus increases the risk of gas