서울대학교 수의과대학 실험동물의학Laboratory Animal Medicine, College of Veterinary Medicine, SNU

Gut microbiome-derived butyrate inhibits the immunosuppressive factors PD-L1 and IL-10 in tumor-associated macrophages in gastr

Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo

Long-term Multimodal Recording Reveals Epigenetic Adaptation Routes in Dormant Breast Cancer Cells

YAP1 induces bladder cancer progression and promotes immune evasion through IL-6/STAT3 pathway and CXCL deregulation

Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway

Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance

The ubiquitin ligase MDM2 sustains STAT5 stability to control T cell-mediated antitumor immunity

Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines

Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cel

Immune evasion of dormant disseminated tumor cells is due to their scarcity and can be overcome by T cell immunotherapies