Professor
D.V.M, Ph.D, DKCLAM
박준원 Jun Won Park
Education
2003.03 ~ 2009.02 : College of Veterinary Medicine, Seoul National University, Seoul, Korea, D.V.M.
2009.03 ~ 2014.02 : Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Seoul, Korea, M.S./Ph.D.
Career as a P.I.
2019.03 ~ 2024.02 : Assistant professor, Division of Biomedical Convergence, College of Biomedical Science, Kangwon National University, Chuncheon, Korea
2024.03 ~ Current : Assistant professor, Department of Laboratory Animal Medicine, College of Veterinary Medicine, Seoul National University, Seoul, Korea
Lab member
▶ Research on cancer heterogeneity induced by driver gene mutations (e.g., SMAD4) using genetically engineered mice and organoids.
▶ Laboratory Animal Toxicologic Pathology
▶ Identification of WNT Signaling Pathway Regulators in Gastric Cance
▶ Development and Mechanistic Study of Animal Models for Post-Acute Sequelae of Long COVIDy
▶ Discovering immune checkpoint molecules by modulating cytotoxic T lymphocyte (CTL) functions in gastric cancer.
▶ Suggesting personalized treatment strategies according to driver gene mutation profiles.
Multi-Step Carcinogenesis in Gastric Cancer:
▶ Introduction of Somatic Mutations: Using AAV to introduce mutations into driver genes.
▶ Discovery of Key Metastasis Factors: Identifying critical elements that influence gastric cancer metastasis.
▶ Discovery of cancer metastasis factors, immune checkpoint therapy response factors, drug resistance factors, and antigen mimicry factors between external viruses and cancer through in vivo genome-wide CRISPR screening.
▶ Development of treatment based on the impact and mechanisms of COVID-19 infection on cancer metastasis.
▶ Investigating Microbiome Changes and Roles in Gastric Cancer Induced by Bacteria and Genetic Mutations
▶ Establishment and Optimization of High-Quality Pathological Analysis System for Non-human Primate and Rodent Models
